Projects per year
Organization profile
Organization profile
The Center for Injury Biomechanics, Materials and Medicine (CIBM3) is a multi- and interdisciplinary research center focused on understanding, diagnosing and treating brain injuries and concussions using experimental and computational methods. The CIBM3 is involved in both traumatic brain injury (TBI), a major concern among U.S. soldiers and veterans, and mild TBI and concussion in sports injuries, which also raise serious health concerns. Specifically, through novel blast-tube and drop-tower facilities, we examine what type of helmets, pads and configurations offer the right protection for soldiers and players. We study when and how concussions are caused and if there are simple diagnostic methods to identify concussions. We use animal models and mechanical surrogates to examine the role of blast pressures and the height of falls to relate injury to medical outcomes. Some of our recently funded efforts include examining the effect of blast overpressures on the dose-response curve of animal models and research into the mechanisms of blast-induced brain injury. In yet another project, we use experimental methods to study the effect of eyewear and hearing protection on the TBI susceptibility of warfighters. Namas Chandra, Bryan Pfister, and James Haorah, along with other colleagues from NJIT, medical schools, and Veterans Administration facilities take a holistic approach to offer new measurement techniques, diagnostics, and prognostic tools to address sports injuries and military medicine.
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Collaborations and top research areas from the last five years
Profiles
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Fundamental Understanding of the Mechanism of Cavitation, One of Possible Mechanisms of Blast-Induced Traumatic
Chandra, N. (PI)
8/13/15 → …
Project: Research project
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Brain macrophages after brain injury leads to negative behavioral outcomes
Chandra, N. (PI)
National Institute of Neurological Disorders and Stroke
8/1/21 → 7/31/24
Project: Research project
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High-Power Laser Science Collaboratory
Paul, P. P. S. (PI), Chandra, N. (CoPI), Hay, B. B. (CoPI), Umstadter, D. D. (CoPI), Wedige, A. A. D. (CoPI), Johnson, R. R. C. (CoPI), Chandra, N. N. (CoPI) & Manderscheid, D. D. (CoPI)
9/15/10 → 8/31/13
Project: Research project
Research output
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MCC950 Attenuates Microglial NLRP3-Mediated Chronic Neuroinflammation and Memory Impairment in a Rat Model of Repeated Low-Level Blast Exposure
Ravula, A. R., Murray, K. E., Rao, K. V. R., Pfister, B. J., Citron, B. A. & Chandra, N., Jun 18 2024, In: Journal of Neurotrauma. 41, 11-12, p. 1450-1468 19 p.Research output: Contribution to journal › Article › peer-review
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Plant-Derived Zein as an Alternative to Animal-Derived Gelatin for Use as a Tissue Engineering Scaffold
Limaye, A., Perumal, V., Karner, C. M. & Livingston Arinzeh, T., Mar 2024, In: Advanced NanoBiomed Research. 4, 3, 2300104.Research output: Contribution to journal › Article › peer-review
Open Access -
Acute metabolic alterations in the hippocampus are associated with decreased acetylation after blast induced TBI
Kumari, M., Arora, P., Sharma, P., Hasija, Y., Rana, P., D’souza, M. M., Chandra, N. & Trivedi, R., Jan 2023, In: Metabolomics. 19, 1, 5.Research output: Contribution to journal › Article › peer-review
6 Scopus citations
Press/Media
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Data on Military and Defense Detailed by a Researcher at New Jersey Institute of Technology (Temporal Changes in Functional and Structural Neuronal Activities in Auditory System in Non-Severe Blast-Induced Tinnitus)
10/9/23
1 item of Media coverage
Press/Media: Press / Media
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Research from New Jersey Institute of Technology Reveals New Findings on Brain Injury (Transferrin-Grafted Albumin Nanoparticles for the Targeted Delivery of Apocynin and Neuroprotection in an In Vitro Model of the BBB)
4/10/23
1 item of Media coverage
Press/Media: Press / Media
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Reports from New Jersey Institute of Technology Highlight Recent Research in Traumatic Brain Injury (Enhanced Targeted Delivery of Minocycline via Transferrin Conjugated Albumin Nanoparticle improves Neuroprotection in a Blast Traumatic Brain ...)
3/13/23
1 item of Media coverage
Press/Media: Press / Media