In this paper, we propose a framework to help evaluate the cost and utility of cyber agility maneuvers within networks that have constrained resources such as bandwidth and energy (e.g., MANETs). Many new methods of cyber agility and defensive maneuvers have been proposed; however, a framework to evaluate cost and utility of these maneuvers in the context of mission success is lacking. We outline preliminary considerations such as mission goals, operating conditions and maneuvers to be evaluated. Then, we introduce notional measures of health, security and capability and their interrelationship resulting in an initial framework design. A simple defensive cyber operation of securing a critical communication path for some time duration, both with and without the presence of a detected infection, is provided to illustrate the framework components and mission considerations that must be made before selecting a sequence of maneuvers.