A high-content screening assay for small-molecule modulators of oncogene-induced senescence

Keyphrases

• Oncogene-induced Senescence 100%
• High-content Assay 100%
• Small Molecule Modulators 100%
• Senescence 60%
• Oncogene 40%
• Cellular Senescence 40%
• Signaling Pathway 20%
• Downstream Signaling 20%
• Mammalian Cells 20%
• Imaging Systems 20%
• Signaling Events 20%
• Protein Kinase 20%
• Oncogenic Ras 20%
• β-Galactosidase (β-Gal) 20%
• Cell Growth Arrest 20%
• Senescence-associated 20%
• Small Molecule Kinase Inhibitors 20%
• Proliferation Inhibition 20%
• Small Molecule Screen 20%
• Cell Transformation 20%
• Induced Senescence 20%
• Screening Platform 20%
• Senescence-associated Heterochromatin Foci 20%
• Primary Fibroblasts 20%
• High-content Imaging 20%
• High-content Screening 20%
• Stable Cells 20%
• Tumor Suppression Mechanism 20%
• Senescence Markers 20%

Pharmacology, Toxicology and Pharmaceutical Science

• High-Content Screening 100%
• Carcinogenesis 50%
• Cancer Inhibition 50%
• Protein Kinases 50%
• Phosphotransferase Inhibitor 50%
• Growth Disorder 50%
• Galactosidase 50%

Biochemistry, Genetics and Molecular Biology

• Small Molecule 100%
• Oncogene 100%
• Cell Growth 14%
• Signal Transduction 14%
• Kinase 14%
• Phosphotransferase 14%
• Carcinogenesis 14%
• Protein Kinases 14%
• Stable Cell 14%
• Cell Transformation 14%
• Heterochromatin 14%
• Fibroblast 14%
• Galactosidase 14%