A Highly Selective Fluorescence Turn-On Sensor for Extracellular Calcium Ion Detection

Binglin Sui, Xinglei Liu, Mengyuan Wang, Kevin D. Belfield

Research output: Contribution to journalArticlepeer-review

20 Scopus citations

Abstract

A highly water-soluble, fluorescence turn-on sensor for Ca2+is reported. The sensor affords high selectivity in sensing Ca2+over other biologically important metal cations. The dissociation constant of the sensor in binding Ca2+is 0.92 mm. Fluorescence microscopy experiments demonstrate that the sensor is cell-impermeable and capable of detecting extracellular Ca2+.

Original languageEnglish (US)
Pages (from-to)10351-10354
Number of pages4
JournalChemistry - A European Journal
Volume22
Issue number30
DOIs
StatePublished - Jul 18 2016

All Science Journal Classification (ASJC) codes

  • Catalysis
  • Organic Chemistry

Keywords

  • calcium
  • cell imaging
  • extracellular calcium detection
  • fluorescence microscopy
  • fluorescence sensors

Fingerprint

Dive into the research topics of 'A Highly Selective Fluorescence Turn-On Sensor for Extracellular Calcium Ion Detection'. Together they form a unique fingerprint.

Cite this