Abstract
The synthesis, structural, and photophysical characterization of a series of new fluorescent donor-acceptor and acceptor-acceptor molecules, based on the fluorenyl ring system, with two-photon absorbing properties is described. These new compounds exhibited large Stokes shifts, high fluorescence quantum yields, and significantly, high two-photon absorption cross sections, making them well suited for two-photon fluorescence microscopy imaging. Confocal and two-photon fluorescence microscopy imaging of COS-7 and HCT 116 cells incubated with probe I showed endosomal selectivity, demonstrating the potential of this class of fluorescent probes in multiphoton fluorescence microscopy.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 3975-3982 |
| Number of pages | 8 |
| Journal | Journal of Organic Chemistry |
| Volume | 75 |
| Issue number | 12 |
| DOIs | |
| State | Published - Jun 18 2010 |
| Externally published | Yes |
All Science Journal Classification (ASJC) codes
- Organic Chemistry
Fingerprint
Dive into the research topics of 'A series of fluorene-based two-photon absorbing molecules: Synthesis, linear and nonlinear characterization, and bioimaging'. Together they form a unique fingerprint.Cite this
- APA
- Author
- BIBTEX
- Harvard
- Standard
- RIS
- Vancouver