A targeted, image-guided and dually locked photoresponsive drug delivery system

S. Karthik, B. N. Prashanth Kumar, Moumita Gangopadhyay, Mahitosh Mandal, N. D.Pradeep Singh

Research output: Contribution to journalArticlepeer-review

20 Scopus citations

Abstract

We have developed a new targeted image-guided photoresponsive drug delivery system (DDS) based on a dual locking strategy. Excitation of the DDS by fluorescent light results in the first unlocking and activation of the drug, and allows real-time monitoring of the prodrug. Extended irradiation results in a second unlocking, giving drug release within cancer cells.

Original languageEnglish (US)
Pages (from-to)728-732
Number of pages5
JournalJournal of Materials Chemistry B
Volume3
Issue number5
DOIs
StatePublished - Feb 7 2015
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Chemistry(all)
  • Biomedical Engineering
  • Materials Science(all)

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