Advanced glycation endproducts for age-at-death estimation

Luis L. Cabo, Christian Thomas, Sara C. Zapico

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations


Age-at-death estimation is one of the fundamental parameters in the forensic sciences to create a biological profile leading to the identification of deceased individuals (Zapico and Ubelaker 2013). Age can be estimated very accurately in childhood using anthropological methods. In contrast, in adulthood, estimation of age-atdeath is influenced by endogenous and exogenous factors, which make an accurate determination difficult (Zapico and Ubelaker 2013). For that reason, new methodologies for age-at-death estimation are being developed based on the natural process of aging, which leads to alterations of tissues and organs at different biochemical levels. One of these alterations can be seen in the study of Advanced Glycation endproducts. Although few studies were conducted with forensic purposes in mind, this chapter will give an overview of different works that correlate AGEs with aging, pointing out their application to forensic science research.

Original languageEnglish (US)
Title of host publicationMechanisms Linking Aging, Diseases and Biological Age Estimation
PublisherCRC Press
Number of pages7
ISBN (Electronic)9781498709705
ISBN (Print)9781498709699
StatePublished - Jan 1 2017
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • General Social Sciences
  • General Medicine
  • General Biochemistry, Genetics and Molecular Biology


  • Advanced glycation endproducts (AGEs)
  • Age-at-death estimation
  • Aging
  • Anthropological methods
  • Bone
  • CML
  • Cartilage
  • Color changes
  • Hippocampal pyramidal neurons
  • Intervertebral discs
  • Lens
  • Maillard reaction
  • Pentoside
  • RAGE
  • Teeth


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