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Alcohol and HIV decrease proteasome and immunoproteasome function in macrophages: Implications for impaired immune function during disease
James Haorah
, David Heilman
, Casey Diekmann
, Natalia Osna
, Terrence M. Donohue
, Anuja Ghorpade
, Yuri Persidsky
Research output
:
Contribution to journal
›
Article
›
peer-review
56
Scopus citations
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Dive into the research topics of 'Alcohol and HIV decrease proteasome and immunoproteasome function in macrophages: Implications for impaired immune function during disease'. Together they form a unique fingerprint.
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Keyphrases
Alcohol
100%
Macrophages
100%
Proteinase
100%
Ethanol
100%
Immunoproteasome
100%
Immune Function
100%
HIV-1 Infection
66%
Monocyte-derived Macrophages
50%
Reactive Oxygen Species
33%
Antigen Presentation
33%
Catalytic Activity
16%
Disease Progression
16%
Human Immunodeficiency Virus Type 1 (HIV-1)
16%
Mononuclear Phagocytes
16%
CYP2E1 Activity
16%
Metabolic Enzymes
16%
Functional Change
16%
Protein Processing
16%
Damaged Proteins
16%
Alcohol Abuse
16%
Immune Process
16%
Antioxidant
16%
Viral Replication
16%
Immunology and Microbiology
Macrophage
100%
Human Immunodeficiency Virus 1
100%
Human Immunodeficiency Virus
100%
Monocyte
60%
Antigen Presentation
40%
Viral Replication
20%
Mononuclear Phagocyte
20%
Protein Processing
20%