The authors review the literature about the problem of the alteration in dissolution characteristics of gelatin-based formulations. This article also includes a brief introduction to gelatin as a pharmaceutical ingredient and describes examples of the altered dissolution profile; the established cause, mechanisms, influencing factors, and stress methods for study of the behavior; methods for determining the nature and extent of the change; and the reported solutions to the problem.
|Original language||English (US)|
|Number of pages||23|
|Journal||Pharmaceutical Technology North America|
|State||Published - Aug 15 2002|
All Science Journal Classification (ASJC) codes
- Pharmaceutical Science