Ammonia-induced activation of p53 in cultured astrocytes: Role in cell swelling and glutamate uptake

Keyphrases

• Induced Activation 100%
• Glutamate Uptake 100%
• Cell Swelling 100%
• Cultured Astrocytes 100%
• Ammonia-induced 100%
• Astrocyte Swelling 85%
• Nitrosative Stress 71%
• Mitogen-activated Protein Kinase 57%
• Mitochondrial Permeability Transition 57%
• Nuclear factor-κB 42%
• Induced Astrocytes 42%
• Downstream Targets 28%
• Hepatic Encephalopathy 28%
• Stress-activated Protein Kinase 28%
• Pifithrin-α 28%
• Ammonia 14%
• Astrocytic 14%
• Transcription Factor 14%
• NF-B 14%
• Astrocytes 14%
• P38 Mitogen-activated Protein Kinase (p38 MAPK) 14%
• Neurological Complications 14%
• Phosphorylation 14%
• Catalase 14%
• Ammonium Chloride 14%
• Protein Factor 14%
• Nitric Oxide Synthase Inhibitors 14%
• L-NAME 14%
• Acute Form 14%
• Ammonia Neurotoxicity 14%
• Acute Liver Failure 14%
• ERK2 14%
• Hyperammonemia 14%
• Uptake Inhibition 14%
• Cytotoxic Brain Edema 14%
• P53 Activation 14%
• Inhibition Process 14%
• Desferrioxamine 14%
• MnTBAP 14%
• Tumor Protein p53 (TP53) 14%
• Elevated Levels 14%
• Phosphorylation Activation 14%
• Antioxidant Vitamin E 14%

Neuroscience

• Astrocyte 100%
• Glutamic Acid 100%
• P53 100%
• Cell Swelling 100%
• Nitrosative Stress 55%
• Mitochondrial Permeability 44%
• Mitogen-Activated Protein Kinase 33%
• Nuclear Factor 33%
• Hepatic Encephalopathy 22%
• C-Jun N-Terminal Kinases 22%
• phosphorylation 22%
• Nitric Oxide Synthase 11%
• Transcription Factors 11%
• Antioxidant 11%
• Neurotoxicity 11%
• Deferoxamine 11%
• Catalase 11%
• Vitamin E 11%
• Mitogen Activated Protein Kinase 3 11%
• P38 Mitogen-Activated Protein Kinases 11%
• [5,10,15,20 Tetrakis(4 Carboxyphenyl) 21h,23h Porphine]manganese(iii) Chloride 11%
• Tumor Suppressor Protein 11%