Abstract
Laplace transforms were used to solve a mathematical model developed for percutaneous drug absorption. The model includes application and removal of the vehicle from the skin. A system of two linear partial differential equations was solved during the application period. The concentration of the medicinal agent in the skin at the end of the application period was then used as initial condition to determine the distribution of the drug in the skin following instantaneous removal of the vehicle. Numerical results of the amount of drug released in both cases are presented.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 303-304 |
| Number of pages | 2 |
| Journal | Proceedings of the IEEE Annual Northeast Bioengineering Conference, NEBEC |
| State | Published - 2003 |
| Event | Proceedings of the IEEE 29th Annual Northeast Bioengineering Conference - Newark, NJ, United States Duration: Mar 22 2003 → Mar 23 2003 |
All Science Journal Classification (ASJC) codes
- Chemical Engineering(all)
- Bioengineering
Keywords
- Laplace transform
- Percutaneous absorption