An analytical solution for percutaneous drug absorption

L. Simon; N. W. Loney

An analytical solution for percutaneous drug absorption

L. Simon, N. W. Loney

Chemical and Materials Engineering

Research output: Contribution to conference › Paper › peer-review

Abstract

Laplace transforms were used to solve a mathematical model developed for percutaneous drug absorption. The model includes application and removal of the vehicle from the skin. A system of two linear partial differential equations was solved during the application period. The concentration of the medicinal agent in the skin at the end of the application period was then used as initial condition to determine the distribution of the drug in the skin following instantaneous removal of the vehicle. Numerical results of the amount of drug released in both cases are presented.

Original language	English (US)
Pages	303-304
Number of pages	2
State	Published - Aug 22 2003
Event	Proceedings of the IEEE 29th Annual Northeast Bioengineering Conference - Newark, NJ, United States Duration: Mar 22 2003 → Mar 23 2003

Other

Other	Proceedings of the IEEE 29th Annual Northeast Bioengineering Conference
Country	United States
City	Newark, NJ
Period	3/22/03 → 3/23/03

All Science Journal Classification (ASJC) codes

Bioengineering

Keywords

Laplace transform
Percutaneous absorption

Fingerprint Dive into the research topics of 'An analytical solution for percutaneous drug absorption'. Together they form a unique fingerprint.

Cite this

@conference{9c17582a19954fe7a7bb4bc5ec5dc353,

title = "An analytical solution for percutaneous drug absorption",

abstract = "Laplace transforms were used to solve a mathematical model developed for percutaneous drug absorption. The model includes application and removal of the vehicle from the skin. A system of two linear partial differential equations was solved during the application period. The concentration of the medicinal agent in the skin at the end of the application period was then used as initial condition to determine the distribution of the drug in the skin following instantaneous removal of the vehicle. Numerical results of the amount of drug released in both cases are presented.",

keywords = "Laplace transform, Percutaneous absorption",

author = "L. Simon and Loney, {N. W.}",

year = "2003",

month = aug,

day = "22",

language = "English (US)",

pages = "303--304",

note = "Proceedings of the IEEE 29th Annual Northeast Bioengineering Conference ; Conference date: 22-03-2003 Through 23-03-2003",

}

TY - CONF

T1 - An analytical solution for percutaneous drug absorption

AU - Simon, L.

AU - Loney, N. W.

PY - 2003/8/22

Y1 - 2003/8/22

N2 - Laplace transforms were used to solve a mathematical model developed for percutaneous drug absorption. The model includes application and removal of the vehicle from the skin. A system of two linear partial differential equations was solved during the application period. The concentration of the medicinal agent in the skin at the end of the application period was then used as initial condition to determine the distribution of the drug in the skin following instantaneous removal of the vehicle. Numerical results of the amount of drug released in both cases are presented.

AB - Laplace transforms were used to solve a mathematical model developed for percutaneous drug absorption. The model includes application and removal of the vehicle from the skin. A system of two linear partial differential equations was solved during the application period. The concentration of the medicinal agent in the skin at the end of the application period was then used as initial condition to determine the distribution of the drug in the skin following instantaneous removal of the vehicle. Numerical results of the amount of drug released in both cases are presented.

KW - Laplace transform

KW - Percutaneous absorption

UR - http://www.scopus.com/inward/record.url?scp=0041657734&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0041657734&partnerID=8YFLogxK

M3 - Paper

AN - SCOPUS:0041657734

SP - 303

EP - 304

T2 - Proceedings of the IEEE 29th Annual Northeast Bioengineering Conference

Y2 - 22 March 2003 through 23 March 2003

ER -