An empirical bayes testing procedure for detecting variants in analysis of next generation sequencing data

Keyphrases

• Bayesian False Discovery Rate 20%
• Bayesian Methods 20%
• Empirical Bayes 100%
• First-principles Analysis 20%
• Frequentist Approach 20%
• Frequentist Methods 20%
• Genetic Studies 20%
• Genomic Variants 20%
• Microarray Technology 20%
• Multiple Testing 20%
• Next-generation Sequencing 100%
• Next-generation Sequencing Data 100%
• Nominal Level 20%
• Non-null 20%
• Real-time Data Analysis 20%
• Sequence Data 40%
• Sequencing Studies 40%
• Simulation Study 20%
• Site Information 20%
• Statistical Model 20%
• Statistical Test 20%
• Test Efficiency 40%
• Testing Procedures 100%
• Testing Sites 40%
• Variant Calling 20%

Mathematics

• Bayesian 66%
• Empirical Bayes Procedure 100%
• False Discovery Rate 33%
• Frequentist Approach 33%
• Frequentist Method 33%
• Multiple Testing 33%
• Nominal Level 33%
• Real Data 33%
• Simulation Study 33%
• Step Analysis 33%
• Testing Procedure 100%

Computer Science

• False Discovery 33%
• Multiplicity 33%
• Simulation Study 33%
• Statistical Model 33%
• Testing Procedure 100%