An in vitro uniaxial stretch model for axonal injury

Bryan J. Pfister, Timothy P. Weihs, Michael Betenbaugh, Gang Bao

Research output: Contribution to journalArticlepeer-review

115 Scopus citations


A uniaxial stretching device was developed to better tudy neural cell death due to traumatic head injury. Using displacement control rather than force control, this device was capable of achieving strains >70% and strain rates up to 90 s-1. It was demonstrated that the prespecified displacement profiles can be realized almost precisely, and the stretching deformation generated by the device was uniaxial, uniform, and highly reproducible.

Original languageEnglish (US)
Pages (from-to)589-598
Number of pages10
JournalAnnals of Biomedical Engineering
Issue number5
StatePublished - 2003
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Biomedical Engineering


  • Biomechanics
  • Diffuse axonal injury
  • Neural cell death
  • Traumatic brain injury
  • Uniaxial stretch


Dive into the research topics of 'An in vitro uniaxial stretch model for axonal injury'. Together they form a unique fingerprint.

Cite this