Biodegradation of mixed wastes in continuously operated cyclic reactors

Kung Wei Wang, Dimitrios M. Tsangaris, Basil C. Baltzis, Gordon A. Lewandowski

Research output: Contribution to journalArticlepeer-review

5 Scopus citations


The problem of simultaneous biodegradation of two dissimilar substrates in a continuously operated cyclic reactor was studied both at the theoretical and experimental levels using a simple model system. The system involved media containing mixtures of glucose and phenol as carbon sources. A pure culture of Pseudomonas putida (ATCC17514) was employed. Independent kinetic experiments have revealed that glucose and phenol are involved in a crossinhibitory uncompetitive kinetic interaction. The dynamics of a cyclically operated reactor were analyzed using the principles of bifurcation theory for forced systems. Experimental results have confirmed the theoretical predictions. Implications of the results for the design of waste-treating facilities are discussed.

Original languageEnglish (US)
Pages (from-to)803-815
Number of pages13
JournalApplied Biochemistry and Biotechnology - Part A Enzyme Engineering and Biotechnology
StatePublished - 1996

All Science Journal Classification (ASJC) codes

  • Applied Microbiology and Biotechnology
  • Bioengineering
  • Molecular Biology
  • Biochemistry
  • Biotechnology


  • Biodegradation
  • Bioreactor dynamics
  • Cyclic bioreactors
  • Glucose/phenol removal
  • Mixed wastes


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