Block copolymers containing (R)-3-hydroxybutyrate and isosorbide succinate or (S)-lactic acid mers

Romeu Casarano, Denise F.S. Petri, Michael Jaffe, Luiz H. Catalani

    Research output: Contribution to journalArticlepeer-review

    7 Scopus citations


    A new aliphatic block copolyester was synthesized in bulk from transesterification techniques between poly((R)-3-hydroxybutyrate) (PHB) and poly(isosorbide succinate) (PIS). Additionally, other two block copolyesters were synthesized in bulk either from transesterification reactions involving PHB and poly(l-lactide) (PLLA) or from ring-opening copolymerization of l-lactide and hydroxyl-terminated PHB, as result of a previous transesterification reactions with isosorbide. Two-component blends of PHB and PIS or PLLA were also prepared as comparative systems. SEC, MALDI-TOF mass spectrometry (MALDI-TOFMS), 1H and 13C NMR spectroscopy, WAXD, solubility tests, and TG thermal analysis were used for characterization. The block copolymer structures of the products were evidenced by MALDI-TOFMS, 13C NMR, and WAXD data. The block copolymers and the corresponding binary blends presented different solubility properties, as revealed by solubility tests. Although the incorporation of PIS sequences into PHB main backbone did not enhance the thermal stability of the product, it reduced its crystallinity, which could be advantageous for faster biodegradation rate. These products, composed of PHB and PIS or PLLA sequences, are an interesting alternative in biomedical applications.

    Original languageEnglish (US)
    Pages (from-to)33-44
    Number of pages12
    JournalJournal of Polymers and the Environment
    Issue number1
    StatePublished - Mar 2010

    All Science Journal Classification (ASJC) codes

    • Environmental Engineering
    • Polymers and Plastics
    • Materials Chemistry


    • Isosorbide
    • PHB
    • PLLA


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