TY - JOUR
T1 - Building a model of the brain
T2 - from detailed connectivity maps to network organization
AU - Shimoura, Renan Oliveira
AU - Pena, Rodrigo F.O.
AU - Lima, Vinicius
AU - Kamiji, Nilton L.
AU - Girardi-Schappo, Mauricio
AU - Roque, Antonio C.
N1 - Publisher Copyright:
© 2021, The Author(s), under exclusive licence to EDP Sciences, Springer-Verlag GmbH Germany, part of Springer Nature.
PY - 2021/10
Y1 - 2021/10
N2 - The field of computational modeling of the brain is advancing so rapidly that now it is possible to model large scale networks representing different brain regions with a high level of biological detail in terms of numbers of neurons and synapses. For a theoretician approaching a neurobiological question, it is important to analyze the pros and cons of each of the models available. Here, we provide a tutorial review on recent models for different brain circuits, which are based on experimentally obtained connectivity maps. We discuss particularities that may be relevant to the modeler when choosing one of the reviewed models. The objective of this review is to give the reader a fair notion of the computational models covered, with emphasis on the corresponding connectivity maps, and how to use them.
AB - The field of computational modeling of the brain is advancing so rapidly that now it is possible to model large scale networks representing different brain regions with a high level of biological detail in terms of numbers of neurons and synapses. For a theoretician approaching a neurobiological question, it is important to analyze the pros and cons of each of the models available. Here, we provide a tutorial review on recent models for different brain circuits, which are based on experimentally obtained connectivity maps. We discuss particularities that may be relevant to the modeler when choosing one of the reviewed models. The objective of this review is to give the reader a fair notion of the computational models covered, with emphasis on the corresponding connectivity maps, and how to use them.
UR - http://www.scopus.com/inward/record.url?scp=85107817296&partnerID=8YFLogxK
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U2 - 10.1140/epjs/s11734-021-00152-7
DO - 10.1140/epjs/s11734-021-00152-7
M3 - Review article
AN - SCOPUS:85107817296
SN - 1951-6355
VL - 230
SP - 2887
EP - 2909
JO - European Physical Journal: Special Topics
JF - European Physical Journal: Special Topics
IS - 14-15
ER -