Collaborative and trajectory prediction models of medical conditions by mining patients' Social Data

Xiang Ji, Soon Ae Chun, James Geller, Vincent Oria

Research output: Chapter in Book/Report/Conference proceedingConference contribution

10 Scopus citations

Abstract

In the U.S., 80% of Medicare spending is for managing patients with multiple coexisting conditions. Predicting potentially correlated diseases for an individual patient and correlated disease progression paths are both important research tasks. For example, obese patients are at an increased risk for developing type-2 diabetes and hypertension. This correlation is called comorbidity relationship. Discovering the comorbidity relationships is complex and difficult due to the limited access to Electronic Health Records by privacy laws. In this paper, we present a framework called Social Data-based Prediction of Incidence and Trajectory to predict potential risks for medical conditions as well as its progression trajectory to identify the comorbidity path. The framework utilizes patients' publicly available social media data and presents a collaborative prediction model to predict the ranked list of potential comorbidity incidences, and a trajectory prediction model to reveal different paths of condition progression. The experimental results show that our framework is able to predict future conditions for online patients with a coverage value of 48% and 75% for a top-20 and a top-100 ranked list, respectively. For risk trajectory prediction, our framework is able to reveal each potential progression trajectory between any two conditions and infer the confidence of the future trajectory, given any observed condition. The predicted trajectories are validated with existing comorbidity relations from the medical literature.

Original languageEnglish (US)
Title of host publicationProceedings - 2015 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2015
Editorslng. Matthieu Schapranow, Jiayu Zhou, Xiaohua Tony Hu, Bin Ma, Sanguthevar Rajasekaran, Satoru Miyano, Illhoi Yoo, Brian Pierce, Amarda Shehu, Vijay K. Gombar, Brian Chen, Vinay Pai, Jun Huan
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages695-700
Number of pages6
ISBN (Electronic)9781467367981
DOIs
StatePublished - Dec 16 2015
EventIEEE International Conference on Bioinformatics and Biomedicine, BIBM 2015 - Washington, United States
Duration: Nov 9 2015Nov 12 2015

Publication series

NameProceedings - 2015 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2015

Other

OtherIEEE International Conference on Bioinformatics and Biomedicine, BIBM 2015
Country/TerritoryUnited States
CityWashington
Period11/9/1511/12/15

All Science Journal Classification (ASJC) codes

  • Software
  • Artificial Intelligence
  • Health Informatics
  • Biomedical Engineering

Keywords

  • Collaborative Prediction
  • Disease Progression
  • Mining Social Media
  • Predictive Analytics
  • Trajectory Prediction

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