Common-path Fourier-domain optical coherence tomography in ophthalmology applications

Jae Ho Han; Xuan Liu; Kang Zhang; Jin U. Kang

doi:10.1109/LISSA.2009.4906735

Common-path Fourier-domain optical coherence tomography in ophthalmology applications

Jae Ho Han, Xuan Liu, Kang Zhang, Jin U. Kang

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

We have demonstrated in vivo three-dimensional imaging and estimated localized and quantitative hemoglobin oxygen saturation (SO₂) of blood vessel by using a simple, easy to operate common-path Fourier-domain optical coherence tomography (OCT) system. The common-path OCT system can be easily integrated with various surgical tools and we demonstrated its usefulness by imaging outer and inner intraocular tissues such as cornea and neurosensory retinal layers as well as detecting SO₂ level from a chicken embryo. The system uses 800nm near infrared broadband light sources and has axial resolution as low as 3μm in air. Self-adaptive scanning mechanism with real-time surface recognition and feedback control was also applied to the probe where the scanning probe tracks the sample surface variance and effective imaging depth was largely extended to the probe's free-moving range.

Original language	English (US)
Title of host publication	2009 IEEE/NIH Life Science Systems and Applications Workshop, LiSSA 2009
Pages	163-166
Number of pages	4
DOIs	https://doi.org/10.1109/LISSA.2009.4906735
State	Published - Jul 23 2009
Externally published	Yes
Event	2009 IEEE/NIH Life Science Systems and Applications Workshop, LiSSA 2009 - Bethesda, MD, United States Duration: Apr 9 2009 → Apr 10 2009

Other

Other	2009 IEEE/NIH Life Science Systems and Applications Workshop, LiSSA 2009
Country/Territory	United States
City	Bethesda, MD
Period	4/9/09 → 4/10/09

All Science Journal Classification (ASJC) codes

Computational Theory and Mathematics
Biomedical Engineering
Electrical and Electronic Engineering

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10.1109/LISSA.2009.4906735

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title = "Common-path Fourier-domain optical coherence tomography in ophthalmology applications",

abstract = "We have demonstrated in vivo three-dimensional imaging and estimated localized and quantitative hemoglobin oxygen saturation (SO2) of blood vessel by using a simple, easy to operate common-path Fourier-domain optical coherence tomography (OCT) system. The common-path OCT system can be easily integrated with various surgical tools and we demonstrated its usefulness by imaging outer and inner intraocular tissues such as cornea and neurosensory retinal layers as well as detecting SO2 level from a chicken embryo. The system uses 800nm near infrared broadband light sources and has axial resolution as low as 3μm in air. Self-adaptive scanning mechanism with real-time surface recognition and feedback control was also applied to the probe where the scanning probe tracks the sample surface variance and effective imaging depth was largely extended to the probe's free-moving range.",

author = "Han, {Jae Ho} and Xuan Liu and Kang Zhang and Kang, {Jin U.}",

year = "2009",

month = jul,

day = "23",

doi = "10.1109/LISSA.2009.4906735",

language = "English (US)",

isbn = "9781424442935",

pages = "163--166",

booktitle = "2009 IEEE/NIH Life Science Systems and Applications Workshop, LiSSA 2009",

note = "2009 IEEE/NIH Life Science Systems and Applications Workshop, LiSSA 2009 ; Conference date: 09-04-2009 Through 10-04-2009",

}

Han, JH, Liu, X, Zhang, K & Kang, JU 2009, Common-path Fourier-domain optical coherence tomography in ophthalmology applications. in 2009 IEEE/NIH Life Science Systems and Applications Workshop, LiSSA 2009., 4906735, pp. 163-166, 2009 IEEE/NIH Life Science Systems and Applications Workshop, LiSSA 2009, Bethesda, MD, United States, 4/9/09. https://doi.org/10.1109/LISSA.2009.4906735

TY - GEN

T1 - Common-path Fourier-domain optical coherence tomography in ophthalmology applications

AU - Han, Jae Ho

AU - Liu, Xuan

AU - Zhang, Kang

AU - Kang, Jin U.

PY - 2009/7/23

Y1 - 2009/7/23

N2 - We have demonstrated in vivo three-dimensional imaging and estimated localized and quantitative hemoglobin oxygen saturation (SO2) of blood vessel by using a simple, easy to operate common-path Fourier-domain optical coherence tomography (OCT) system. The common-path OCT system can be easily integrated with various surgical tools and we demonstrated its usefulness by imaging outer and inner intraocular tissues such as cornea and neurosensory retinal layers as well as detecting SO2 level from a chicken embryo. The system uses 800nm near infrared broadband light sources and has axial resolution as low as 3μm in air. Self-adaptive scanning mechanism with real-time surface recognition and feedback control was also applied to the probe where the scanning probe tracks the sample surface variance and effective imaging depth was largely extended to the probe's free-moving range.

AB - We have demonstrated in vivo three-dimensional imaging and estimated localized and quantitative hemoglobin oxygen saturation (SO2) of blood vessel by using a simple, easy to operate common-path Fourier-domain optical coherence tomography (OCT) system. The common-path OCT system can be easily integrated with various surgical tools and we demonstrated its usefulness by imaging outer and inner intraocular tissues such as cornea and neurosensory retinal layers as well as detecting SO2 level from a chicken embryo. The system uses 800nm near infrared broadband light sources and has axial resolution as low as 3μm in air. Self-adaptive scanning mechanism with real-time surface recognition and feedback control was also applied to the probe where the scanning probe tracks the sample surface variance and effective imaging depth was largely extended to the probe's free-moving range.

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U2 - 10.1109/LISSA.2009.4906735

DO - 10.1109/LISSA.2009.4906735

M3 - Conference contribution

AN - SCOPUS:67650657202

SN - 9781424442935

SP - 163

EP - 166

BT - 2009 IEEE/NIH Life Science Systems and Applications Workshop, LiSSA 2009

T2 - 2009 IEEE/NIH Life Science Systems and Applications Workshop, LiSSA 2009

Y2 - 9 April 2009 through 10 April 2009

ER -

Common-path Fourier-domain optical coherence tomography in ophthalmology applications

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