Common-path Fourier-domain optical coherence tomography in ophthalmology applications

Jae Ho Han, Xuan Liu, Kang Zhang, Jin U. Kang

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2 Scopus citations

Abstract

We have demonstrated in vivo three-dimensional imaging and estimated localized and quantitative hemoglobin oxygen saturation (SO2) of blood vessel by using a simple, easy to operate common-path Fourier-domain optical coherence tomography (OCT) system. The common-path OCT system can be easily integrated with various surgical tools and we demonstrated its usefulness by imaging outer and inner intraocular tissues such as cornea and neurosensory retinal layers as well as detecting SO2 level from a chicken embryo. The system uses 800nm near infrared broadband light sources and has axial resolution as low as 3μm in air. Self-adaptive scanning mechanism with real-time surface recognition and feedback control was also applied to the probe where the scanning probe tracks the sample surface variance and effective imaging depth was largely extended to the probe's free-moving range.

Original languageEnglish (US)
Title of host publication2009 IEEE/NIH Life Science Systems and Applications Workshop, LiSSA 2009
Pages163-166
Number of pages4
DOIs
StatePublished - Jul 23 2009
Externally publishedYes
Event2009 IEEE/NIH Life Science Systems and Applications Workshop, LiSSA 2009 - Bethesda, MD, United States
Duration: Apr 9 2009Apr 10 2009

Other

Other2009 IEEE/NIH Life Science Systems and Applications Workshop, LiSSA 2009
CountryUnited States
CityBethesda, MD
Period4/9/094/10/09

All Science Journal Classification (ASJC) codes

  • Computational Theory and Mathematics
  • Biomedical Engineering
  • Electrical and Electronic Engineering

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