Comparison between three-dimensional strain in the anterior and posterior walls during left ventricular ejection

J. M. Guccione, W. G. O'Dell, A. S. Douglas, William Hunter

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

We examined the pattern of deformation in the anterior and posterior free walls of the normal left ventricle for a wide range of chamber volumes before and after ejection (pre- and afterloads) under well-defined boundary conditions. Local three-dimensional Lagrangian strains in four isolated, blood-perfused dog hearts were measured by biplane cineradiography of radiopaque beads implanted between midwall and the outside surface (epicardium) at both sites. Anterior and posterior subepicardial strains throughout various cardiac cycles were computed with respect to the state at which the left ventricle was filled to its maximum volume. During ejection, the approximately linear relations between all six strain components for either site and left ventricular volume (V) were nearly independent of preload and afterload, similar to previous observations in the lateral wall. On average, mean meridional (E22) and radial strains during ejection (E33) were significantly greater in the anterior wall (-0.045±0.006 and 0.183±0.022) than in the posterior wall (-0.024±0.007 and 0.093±0.013). In all four hearts, the mean transverse shear strain during ejection E23 was significantly different on the anterior (-0.023±0.011) and posterior walls (-0.034±0.009). Also, changes in three of the six strain components with ejected volume (ΔE33/ΔV, ΔE12/ΔV, ΔE13/ΔV) varied significantly between the anterior (-0.0108±0.0011, -0.0067±0.0003, 0.0014±0.0006 ml-1) and posterior subepicardium (-0.0059±0.0006, -0.0018±0.0001, -0.0001±0.0007 ml-1). Left ventricular geometric differences i.e., the rather flat posterior free wall, may be responsible for these variations.

Original languageEnglish (US)
Title of host publication1992 Advances in Bioengineering
PublisherPubl by ASME
Pages465-468
Number of pages4
Volume22
ISBN (Print)0791811166
StatePublished - Dec 1 1992
Externally publishedYes
EventWinter Annual Meeting of the American Society of Mechanical Engineers - Anaheim, CA, USA
Duration: Nov 8 1992Nov 13 1992

Other

OtherWinter Annual Meeting of the American Society of Mechanical Engineers
CityAnaheim, CA, USA
Period11/8/9211/13/92

All Science Journal Classification (ASJC) codes

  • Engineering(all)

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