Comparison of Binding Site of Remdesivir and Its Metabolites with NSP12-NSP7-NSP8, and NSP3 of SARS CoV-2 Virus and Alternative Potential Drugs for COVID-19 Treatment

Keyphrases

• SARS-CoV-2 Virus 100%
• Binding Site 100%
• Potential Drugs 100%
• COVID-19 Treatment 100%
• Nsp12 100%
• Nsp3 100%
• Nsp7 100%
• Remdesivir 100%
• Spike Protein 40%
• Virus Spike 30%
• COVID-19 20%
• FDA-approved Drugs 20%
• Top 10 20%
• ADP-ribose 20%
• Severe Disease 10%
• Coronavirus 10%
• Potential Activity 10%
• Emergency Department Use 10%
• Infectivity 10%
• Monophosphate 10%
• Immunization 10%
• GS-441524 10%
• ChemScore 10%
• G-score 10%
• D614G mutation 10%
• Docking Score 10%
• Alternative Treatment Methods 10%
• S1 Shedding 10%
• Docking Approach 10%
• Structure-based Docking 10%
• D-score 10%
• Child Hospitalized 10%

Pharmacology, Toxicology and Pharmaceutical Science

• Binding Site 100%
• SARS Coronavirus 100%
• Remdesivir 100%
• Virus Spike Protein 33%
• Adenosine Diphosphate Ribose 22%
• Adenosine Phosphate 22%
• Disease 11%
• Infection 11%
• Coronavirinae 11%
• Severe Acute Respiratory Syndrome 11%