Complex 3D bioprinting methods

Research output: Contribution to journalReview articlepeer-review

46 Scopus citations


3D bioprinting technology is evolving in complexity to enable human-scale, high-resolution, and multi-cellular constructs to better mimic the native tissue microenvironment. The ultimate goal is to achieve necessary complexity in the bioprinting process to biomanufacture fully-functional tissues and organs to address organ shortage and lack of patient-specific disease models. In this Review, we presented an in-depth overview of complex 3D bioprinting approaches including evolution of complex bioprinting, from simple gel-casting approach to multi-material bioprinting to omnidirectional bioprinting approaches, and emerging bioprinting approaches, including 4D bioprinting and in situ bioprinting technologies.

Original languageEnglish (US)
Article number011508
JournalAPL Bioengineering
Issue number1
StatePublished - Mar 1 2021

All Science Journal Classification (ASJC) codes

  • Bioengineering
  • Biophysics
  • Biomedical Engineering
  • Biomaterials


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