@inproceedings{9614dce16fb34faeb16ee8f281c841bd,
title = "Computational simulation of the deformation of neuronal cells",
abstract = "A numerical simulation (finite element method (FEM)) is used to determine the local mechanical response of a neuron based on the real neuron geometry. The real 3D geometry of a neuron can be constructed from the 2D confocal image stack which is taken per micron along the thickness direction from the top surface of neuron to the substrate. By matching the simulated deformation of the neuron with the measured results from the confocal microscopy images, the relative strength of the neuron components can be determined based on the reverse analysis of FEM. Then, the neuron local mechanical response and the relationship between the local response and the global applied deformation can be obtained, which will be the first step of building the mechanical injury model of neuron.",
author = "Guoxin Cao and You Zhou and Lee, {Jeong Soon} and Lim, {Jung Yul} and Shailesh Ganpule and Namas Chandra",
year = "2010",
doi = "10.1115/IMECE2010-37949",
language = "English (US)",
isbn = "9780791844267",
series = "ASME International Mechanical Engineering Congress and Exposition, Proceedings (IMECE)",
publisher = "American Society of Mechanical Engineers (ASME)",
pages = "179--180",
booktitle = "Biomedical and Biotechnology Engineering",
note = "ASME 2010 International Mechanical Engineering Congress and Exposition, IMECE 2010 ; Conference date: 12-11-2010 Through 18-11-2010",
}