Computer-based model of the Cerebro-Spinal Fluid dynamics coupled to the cardiac cycle

B. Mantilla, J. Steffener, W. Hunter

Research output: Contribution to journalConference articlepeer-review

Abstract

Cerebro-Spinal Fluid (CSF) flow dynamics have not been fully explained in terms of the physical forces that interact to propel CSF through the different cavities of the brain and spine. A complex CSF flow pattern has been identified and documented by cine-MRI and related in time to cardiac cycle. A hypothesis based on the concept of cyclical brain-compliance variation dependent on the cardiac cycle as the mechanism driving CSF is presented. A computer-based model explaining the relation between the cardiac cycle and CSF flow is presented as well.

Original languageEnglish (US)
Article number12.1.3
Pages (from-to)233-234
Number of pages2
JournalBioengineering, Proceedings of the Northeast Conference
StatePublished - Dec 12 2005
EventProceedings of the 2005 IEEE 31st Annual Northeast Bioengineering Conference - Hoboken, NJ, United States
Duration: Apr 2 2005Apr 3 2005

All Science Journal Classification (ASJC) codes

  • Bioengineering

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