Abstract
RNA secondary structure prediction has been studied for quite awhile. Many minimum free energy (MFE) methods have been developed for predicting the secondary structures of single RNA sequences, such as mfold [1], RNAfold [2], MPGAfold [3], as well as recent tools presented in the literature [4, 5]. However, the accuracy of predicted structures is far from perfect. As evaluated by Gardner and Giegerich [6], the accuracy of the MFE methods for single sequences is 73% when averaged over many different RNAs.
| Original language | English (US) |
|---|---|
| Title of host publication | Biological Data Mining |
| Publisher | CRC Press |
| Pages | 1-26 |
| Number of pages | 26 |
| ISBN (Electronic) | 9781420086850 |
| ISBN (Print) | 9781420086843 |
| State | Published - Jan 1 2009 |
All Science Journal Classification (ASJC) codes
- General Computer Science
- General Agricultural and Biological Sciences
- General Biochemistry, Genetics and Molecular Biology