Control of Alzheimer's amyloid beta toxicity by the high molecular weight immunophilin FKBP52 and copper homeostasis in Drosophila

Keyphrases

• Drosophilidae 100%
• High Molecular Weight 100%
• Alzheimer's Amyloid-β 100%
• Immunophilin 100%
• Copper Homeostasis 100%
• Amyloid Toxicity 100%
• FKBP52 100%
• Alzheimer 16%
• Amyloid Precursor Protein 16%
• Protein Folding 8%
• Hippocampus 8%
• Cell Behavior 8%
• Basal Ganglia 8%
• Overexpression 8%
• Frontal Cortex 8%
• Reconstitution 8%
• Loss Function 8%
• Copper Chelator 8%
• Gain-of-function mutation 8%
• FK506-binding Protein 8%
• Copper Transporter 8%
• Prolyl Isomerase 8%
• Atox1 8%
• Hematopoietic Cells 8%
• Hormone Signaling 8%
• FK506 8%
• Transgenic Drosophila 8%
• PPIase 8%
• PPIase Activity 8%
• Gain-of-function 8%
• Intracellular Copper 8%

Neuroscience

• Beta Amyloid 100%
• Immunophilin 100%
• Amyloid Precursor Protein 66%
• Cell Function 33%
• Hippocampus 33%
• Frontal Lobe 33%
• Basal Ganglia 33%
• Loss of Function Mutation 33%
• Tacrolimus 33%
• Protein Folding 33%
• Chelating Agent 33%
• Isomerase 33%
• Fk 506 Binding Protein 33%
• Proline Derivative 33%

Biochemistry, Genetics and Molecular Biology

• Homeostasis 100%
• Molecular Weight 100%
• FKBP52 100%
• Amyloid Beta 100%
• Immunophilin 100%
• Diptera 16%
• Amyloid Precursor Protein 16%
• Protein Folding 8%
• Cell Function 8%
• Lifespan 8%
• Binding Protein 8%
• Loss of Function Mutation 8%
• Transgenic Drosophila 8%
• Prolyl Isomerase 8%