Coupling Electrochemistry with Probe Electrospray Ionization Mass Spectrometry

Yi Cai; Pengyuan Liu; Michael A. Held; Howard D. Dewald; Hao Chen

doi:10.1002/cphc.201600033

Coupling Electrochemistry with Probe Electrospray Ionization Mass Spectrometry

Yi Cai, Pengyuan Liu, Michael A. Held, Howard D. Dewald, Hao Chen

Research output: Contribution to journal › Article › peer-review

18 Scopus citations

Abstract

A new coupling of electrochemistry with mass spectrometry (MS) using probe electrospray ionization (PESI) is presented. Due to the high salt tolerance of PESI, the detection of electrochemical reaction products in room-temperature ionic liquids (RTILs) is realized for the first time. Furthermore, PESI-MS allows the analysis of electrochemical reaction products on different or multiple electrode surfaces. In addition, peptides and proteins fractionated through isoelectric focusing (IEF) in the presence of an external electric field can also be directly analyzed by using PESI-MS, suggesting a new and rapid characterization means for the IEF technique. This study reveals the versatility of EC/PESI-MS, which could have an impact in electrochemistry and bioanalysis fields.

Original language	English (US)
Pages (from-to)	1104-1108
Number of pages	5
Journal	ChemPhysChem
Volume	17
Issue number	8
DOIs	https://doi.org/10.1002/cphc.201600033
State	Published - Apr 18 2016
Externally published	Yes

All Science Journal Classification (ASJC) codes

Atomic and Molecular Physics, and Optics
Physical and Theoretical Chemistry

Keywords

analytical methods
electrochemical reactions
ionic liquids
mass spectrometry
probe electrospray ionization

Access to Document

10.1002/cphc.201600033

Cite this

@article{29e907e39fbe4cfb8f1b63dda612653a,

title = "Coupling Electrochemistry with Probe Electrospray Ionization Mass Spectrometry",

abstract = "A new coupling of electrochemistry with mass spectrometry (MS) using probe electrospray ionization (PESI) is presented. Due to the high salt tolerance of PESI, the detection of electrochemical reaction products in room-temperature ionic liquids (RTILs) is realized for the first time. Furthermore, PESI-MS allows the analysis of electrochemical reaction products on different or multiple electrode surfaces. In addition, peptides and proteins fractionated through isoelectric focusing (IEF) in the presence of an external electric field can also be directly analyzed by using PESI-MS, suggesting a new and rapid characterization means for the IEF technique. This study reveals the versatility of EC/PESI-MS, which could have an impact in electrochemistry and bioanalysis fields.",

keywords = "analytical methods, electrochemical reactions, ionic liquids, mass spectrometry, probe electrospray ionization",

author = "Yi Cai and Pengyuan Liu and Held, {Michael A.} and Dewald, {Howard D.} and Hao Chen",

note = "Publisher Copyright: {\textcopyright} 2016 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.",

year = "2016",

month = apr,

day = "18",

doi = "10.1002/cphc.201600033",

language = "English (US)",

volume = "17",

pages = "1104--1108",

journal = "ChemPhysChem",

issn = "1439-4235",

publisher = "Wiley-VCH Verlag",

number = "8",

}

TY - JOUR

T1 - Coupling Electrochemistry with Probe Electrospray Ionization Mass Spectrometry

AU - Cai, Yi

AU - Liu, Pengyuan

AU - Held, Michael A.

AU - Dewald, Howard D.

AU - Chen, Hao

PY - 2016/4/18

Y1 - 2016/4/18

N2 - A new coupling of electrochemistry with mass spectrometry (MS) using probe electrospray ionization (PESI) is presented. Due to the high salt tolerance of PESI, the detection of electrochemical reaction products in room-temperature ionic liquids (RTILs) is realized for the first time. Furthermore, PESI-MS allows the analysis of electrochemical reaction products on different or multiple electrode surfaces. In addition, peptides and proteins fractionated through isoelectric focusing (IEF) in the presence of an external electric field can also be directly analyzed by using PESI-MS, suggesting a new and rapid characterization means for the IEF technique. This study reveals the versatility of EC/PESI-MS, which could have an impact in electrochemistry and bioanalysis fields.

AB - A new coupling of electrochemistry with mass spectrometry (MS) using probe electrospray ionization (PESI) is presented. Due to the high salt tolerance of PESI, the detection of electrochemical reaction products in room-temperature ionic liquids (RTILs) is realized for the first time. Furthermore, PESI-MS allows the analysis of electrochemical reaction products on different or multiple electrode surfaces. In addition, peptides and proteins fractionated through isoelectric focusing (IEF) in the presence of an external electric field can also be directly analyzed by using PESI-MS, suggesting a new and rapid characterization means for the IEF technique. This study reveals the versatility of EC/PESI-MS, which could have an impact in electrochemistry and bioanalysis fields.

KW - analytical methods

KW - electrochemical reactions

KW - ionic liquids

KW - mass spectrometry

KW - probe electrospray ionization

UR - http://www.scopus.com/inward/record.url?scp=84958214397&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84958214397&partnerID=8YFLogxK

U2 - 10.1002/cphc.201600033

DO - 10.1002/cphc.201600033

M3 - Article

C2 - 26833903

AN - SCOPUS:84958214397

SN - 1439-4235

VL - 17

SP - 1104

EP - 1108

JO - ChemPhysChem

JF - ChemPhysChem

IS - 8

ER -

Coupling Electrochemistry with Probe Electrospray Ionization Mass Spectrometry

Abstract

All Science Journal Classification (ASJC) codes

Keywords

Access to Document

Other files and links

Fingerprint

Cite this