@inproceedings{91d44405e7274edc849e110bf42805e6,
title = "Crystallization of acetaminophen/poly(ethylene oxide) mixtures",
abstract = "A model drug acetaminophen was mixed with PEO, and the morphology, nucleation numbers, and crystallization kinetics of PEO were altered accordingly. The spherulitic growth rate and isothermal DSC endotherm were analyzed by Hoffman-Lauritzen theory and Avrami theory, respectively. It was found that the fold surface free energy increased significantly with increasing drug content, indicating the chain folding of PEO became much more difficult in the presence of the small molecule drug.",
keywords = "Acetaminophen/APAP, Avrami exponent, Hoffman-Lauritzen theory, Isothermal crystallization, Poly(ethylene oxide)/PEO, Solubility, Spherulite",
author = "Min Yang and Gogos, {Costas G.} and Peng Wang",
year = "2012",
language = "English (US)",
isbn = "9781622760831",
series = "Annual Technical Conference - ANTEC, Conference Proceedings",
pages = "2074--2079",
booktitle = "70th Annual Technical Conference of the Society of Plastics Engineers 2012, ANTEC 2012",
note = "70th Annual Technical Conference of the Society of Plastics Engineers 2012, ANTEC 2012 ; Conference date: 02-04-2012 Through 04-04-2012",
}