Data Driven Approaches to Modeling and Analysis of Bioprocesses: Some Industrial Examples

David Hodge, Laurent Simon, M. Nazmul Karim

Research output: Contribution to journalConference articlepeer-review

6 Scopus citations

Abstract

Data-generated models find numerous applications in areas where the speed of collection and logging data surpasses the ability to analyze it. This work is meant to addresses some of the challenges and difficulties encountered in the practical application of these methods in an industrial setting, and more specifically in the bioprocess industry. Neural network and principal component models are the two topics that are covered in detail in this paper. A review of these modeling technologies as applied to bioprocessing is provided, and three original case studies using industrial fermentation data are presented that utilize these models in the context of prediction and monitoring of bioprocess performance.

Original languageEnglish (US)
Pages (from-to)2062-2076
Number of pages15
JournalProceedings of the American Control Conference
Volume3
StatePublished - Nov 10 2003
Event2003 American Control Conference - Denver, CO, United States
Duration: Jun 4 2003Jun 6 2003

All Science Journal Classification (ASJC) codes

  • Electrical and Electronic Engineering

Keywords

  • Bioprocesses
  • Data Analysis
  • Neural Networks
  • PCA

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