Decoding Fine API Agglomeration as a Key Indicator of Powder Flowability and Dissolution: Impact of Particle Engineering

Keyphrases

• Adverse Impact 16%
• Agglomerates 83%
• Agglomeration 100%
• BCS Class II Drug 16%
• Bulk Density 66%
• Bulk Properties 16%
• Contact Model 33%
• Dimensionless Parameters 16%
• Dissolution Enhancement 16%
• Dissolution Rate 16%
• Dry Coating 100%
• Fenofibrate 16%
• Flow Regime 16%
• Flowability 16%
• Granular Bond number 16%
• Griseofulvin 16%
• Improved Processability 16%
• Interparticle Interactions 33%
• Multiple Flows 16%
• Nanosilica 16%
• Non-triviality 16%
• Order of Magnitude 16%
• Particle Engineering 100%
• Particle Scale 16%
• Powder Cohesion 16%
• Powder Cohesiveness 16%
• Powder Dissolution 100%
• Powder Flowability 100%
• Power-law Correlations 16%
• Scale Measure 16%
• Silica 16%
• Silica Coating 16%
• Surface Coverage 16%
• Surface Dissolution 16%
• Surface Energy 16%
• Surface Hydrophobicity 16%
• Surface Roughness 16%
• Surface Wettability 16%

Engineering

• Area Coverage 25%
• Bond Number 25%
• Bulk Density 100%
• Bulk Property 25%
• Contact Model 50%
• Dimensionless Parameter 25%
• Dissolution Rate 25%
• Energy Surface 25%
• Engineering 100%
• Flow Regime 25%
• Hydrophilicity 25%
• Hydrophobic 50%
• Nano Silica 25%
• Particle Contact 50%
• Processability 100%
• Reduction Ratio 25%

Pharmacology, Toxicology and Pharmaceutical Science

• Fenofibrate 50%
• Griseofulvin 50%
• Hydrophobicity 50%
• Ibuprofen 50%
• Nanosilica 50%
• Power Law 50%
• Silicon Dioxide 100%