Decreased frontal lobe function in people with internet addiction disorder

Jun Liu; Fatema Esmail; Ling Jiang Li; Zhi Feng Kou; Wei Hui Li; Xue Ping Gao; Zhi Yuan Wang; Chang Lian Tan; Yan Zhang; Shun Ke Zhou

doi:10.3969/j.issn.1673-5374.2013.34.006

Decreased frontal lobe function in people with internet addiction disorder

Jun Liu, Fatema Esmail, Ling Jiang Li, Zhi Feng Kou, Wei Hui Li, Xue Ping Gao, Zhi Yuan Wang, Chang Lian Tan, Yan Zhang, Shun Ke Zhou

Research output: Contribution to journal › Article › peer-review

12 Scopus citations

Abstract

In our previous studies, we showed that frontal lobe and brainstem functions were abnormal in online game addicts. In this study, 14 students with Internet addiction disorder and 14 matched healthy controls underwent proton-magnetic resonance spectroscopy to measure cerebral function. Results demonstrated that the ratio of N-acetylaspartate to creatine decreased, but the ratio of cho-line-containing compounds to creatine increased in the bilateral frontal lobe white matter in people with Internet addiction disorder. However, these ratios were mostly unaltered in the brainstem, suggesting that frontal lobe function decreases in people with Internet addiction disorder.

Original language	English (US)
Pages (from-to)	3225-3232
Number of pages	8
Journal	Neural Regeneration Research
Volume	8
Issue number	34
DOIs	https://doi.org/10.3969/j.issn.1673-5374.2013.34.006
State	Published - Dec 5 2013
Externally published	Yes

All Science Journal Classification (ASJC) codes

Developmental Neuroscience

Keywords

Choline-containing compounds
Creatine
Grants-supported paper
Internet addiction disorder
Internet gaming addiction
Magnetic resonance imaging
Magnetic resonance spectroscopy
N-acetylaspartate
Neural regeneration
Neuroregeneration

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10.3969/j.issn.1673-5374.2013.34.006

Cite this

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title = "Decreased frontal lobe function in people with internet addiction disorder",

abstract = "In our previous studies, we showed that frontal lobe and brainstem functions were abnormal in online game addicts. In this study, 14 students with Internet addiction disorder and 14 matched healthy controls underwent proton-magnetic resonance spectroscopy to measure cerebral function. Results demonstrated that the ratio of N-acetylaspartate to creatine decreased, but the ratio of cho-line-containing compounds to creatine increased in the bilateral frontal lobe white matter in people with Internet addiction disorder. However, these ratios were mostly unaltered in the brainstem, suggesting that frontal lobe function decreases in people with Internet addiction disorder.",

keywords = "Choline-containing compounds, Creatine, Grants-supported paper, Internet addiction disorder, Internet gaming addiction, Magnetic resonance imaging, Magnetic resonance spectroscopy, N-acetylaspartate, Neural regeneration, Neuroregeneration",

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AU - Esmail, Fatema

AU - Li, Ling Jiang

AU - Kou, Zhi Feng

AU - Li, Wei Hui

AU - Gao, Xue Ping

AU - Wang, Zhi Yuan

AU - Tan, Chang Lian

AU - Zhang, Yan

AU - Zhou, Shun Ke

PY - 2013/12/5

Y1 - 2013/12/5

N2 - In our previous studies, we showed that frontal lobe and brainstem functions were abnormal in online game addicts. In this study, 14 students with Internet addiction disorder and 14 matched healthy controls underwent proton-magnetic resonance spectroscopy to measure cerebral function. Results demonstrated that the ratio of N-acetylaspartate to creatine decreased, but the ratio of cho-line-containing compounds to creatine increased in the bilateral frontal lobe white matter in people with Internet addiction disorder. However, these ratios were mostly unaltered in the brainstem, suggesting that frontal lobe function decreases in people with Internet addiction disorder.

AB - In our previous studies, we showed that frontal lobe and brainstem functions were abnormal in online game addicts. In this study, 14 students with Internet addiction disorder and 14 matched healthy controls underwent proton-magnetic resonance spectroscopy to measure cerebral function. Results demonstrated that the ratio of N-acetylaspartate to creatine decreased, but the ratio of cho-line-containing compounds to creatine increased in the bilateral frontal lobe white matter in people with Internet addiction disorder. However, these ratios were mostly unaltered in the brainstem, suggesting that frontal lobe function decreases in people with Internet addiction disorder.

KW - Choline-containing compounds

KW - Creatine

KW - Grants-supported paper

KW - Internet addiction disorder

KW - Internet gaming addiction

KW - Magnetic resonance imaging

KW - Magnetic resonance spectroscopy

KW - N-acetylaspartate

KW - Neural regeneration

KW - Neuroregeneration

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Decreased frontal lobe function in people with internet addiction disorder

Abstract

All Science Journal Classification (ASJC) codes

Keywords

Access to Document

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