Design and application of ion concentration polarization for preconcentrating charged analytes

Majid Gholinejad; Ali Jabari Moghadam; Dinh Tuan Phan; Amir K. Miri; Seyed Ali Mousavi Shaegh

doi:10.1063/5.0038914

Design and application of ion concentration polarization for preconcentrating charged analytes

Majid Gholinejad, Ali Jabari Moghadam, Dinh Tuan Phan, Amir K. Miri, Seyed Ali Mousavi Shaegh

Research output: Contribution to journal › Review article › peer-review

22 Scopus citations

Abstract

Micro/nanofluidic devices integrated with ion concentration polarization (ICP) phenomenon have been used to preconcentrate low-abundant molecules for separation and detection purposes. This work reviews ICP-based devices focused on electrokinetic fundamentals of ICP in microfluidics and related design factors. We discuss various designs of ICP devices and then provide insight on the role of design factors in ICP function. In addition, fabrication methods and relevant materials for making ICP devices and nanojunctions are explained. This work provides the most up-to-date applications of ICP with emphasis on active and passive methods in controlling and stabilizing streams of preconcentrated molecules to enhance the separation and detection efficiency in diagnostics, desalination, and electrodialysis.

Original language	English (US)
Article number	051301
Journal	Physics of Fluids
Volume	33
Issue number	5
DOIs	https://doi.org/10.1063/5.0038914
State	Published - May 1 2021
Externally published	Yes

All Science Journal Classification (ASJC) codes

Computational Mechanics
Condensed Matter Physics
Mechanics of Materials
Mechanical Engineering
Fluid Flow and Transfer Processes

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10.1063/5.0038914

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title = "Design and application of ion concentration polarization for preconcentrating charged analytes",

abstract = "Micro/nanofluidic devices integrated with ion concentration polarization (ICP) phenomenon have been used to preconcentrate low-abundant molecules for separation and detection purposes. This work reviews ICP-based devices focused on electrokinetic fundamentals of ICP in microfluidics and related design factors. We discuss various designs of ICP devices and then provide insight on the role of design factors in ICP function. In addition, fabrication methods and relevant materials for making ICP devices and nanojunctions are explained. This work provides the most up-to-date applications of ICP with emphasis on active and passive methods in controlling and stabilizing streams of preconcentrated molecules to enhance the separation and detection efficiency in diagnostics, desalination, and electrodialysis.",

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AU - Gholinejad, Majid

AU - Jabari Moghadam, Ali

AU - Phan, Dinh Tuan

AU - Miri, Amir K.

AU - Mousavi Shaegh, Seyed Ali

PY - 2021/5/1

Y1 - 2021/5/1

N2 - Micro/nanofluidic devices integrated with ion concentration polarization (ICP) phenomenon have been used to preconcentrate low-abundant molecules for separation and detection purposes. This work reviews ICP-based devices focused on electrokinetic fundamentals of ICP in microfluidics and related design factors. We discuss various designs of ICP devices and then provide insight on the role of design factors in ICP function. In addition, fabrication methods and relevant materials for making ICP devices and nanojunctions are explained. This work provides the most up-to-date applications of ICP with emphasis on active and passive methods in controlling and stabilizing streams of preconcentrated molecules to enhance the separation and detection efficiency in diagnostics, desalination, and electrodialysis.

AB - Micro/nanofluidic devices integrated with ion concentration polarization (ICP) phenomenon have been used to preconcentrate low-abundant molecules for separation and detection purposes. This work reviews ICP-based devices focused on electrokinetic fundamentals of ICP in microfluidics and related design factors. We discuss various designs of ICP devices and then provide insight on the role of design factors in ICP function. In addition, fabrication methods and relevant materials for making ICP devices and nanojunctions are explained. This work provides the most up-to-date applications of ICP with emphasis on active and passive methods in controlling and stabilizing streams of preconcentrated molecules to enhance the separation and detection efficiency in diagnostics, desalination, and electrodialysis.

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Design and application of ion concentration polarization for preconcentrating charged analytes

Abstract

All Science Journal Classification (ASJC) codes

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