Abstract
Type I collagen was extruded into well-defined fibers using a novel controlled wet spinning device. The device significantly improved the yield of collagen fibers on the micron scale. Collagen scaffold materials fabricated from the device will provide contact-guided growth of neuronal cultures. Fibers composed of different weight percentages, 75, 2, and 3.4 wt% collagen dispersions, were used to validate Schwann cell alignment along the fibers. Interestingly, the different concentrations of extruded collagen dispersions demonstrated unique morphologies and directed growth patterns of Schwann cells.
Original language | English (US) |
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Title of host publication | 2011 IEEE 37th Annual Northeast Bioengineering Conference, NEBEC 2011 |
DOIs | |
State | Published - Jun 16 2011 |
Event | 37th Annual Northeast Bioengineering Conference, NEBEC 2011 - Troy, NY, United States Duration: Apr 1 2011 → Apr 3 2011 |
Other
Other | 37th Annual Northeast Bioengineering Conference, NEBEC 2011 |
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Country/Territory | United States |
City | Troy, NY |
Period | 4/1/11 → 4/3/11 |
All Science Journal Classification (ASJC) codes
- Bioengineering