Design and characterization of a controlled wet spinning device for collagen fiber fabrication for neural tissue engineering

K. E. DeRosa; M. L. Siriwardane; Bryan Pfister

doi:10.1109/NEBC.2011.5778585

Design and characterization of a controlled wet spinning device for collagen fiber fabrication for neural tissue engineering

K. E. DeRosa, M. L. Siriwardane, Bryan Pfister

Bio-Medical Engineering

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

1 Scopus citations

Abstract

Type I collagen was extruded into well-defined fibers using a novel controlled wet spinning device. The device significantly improved the yield of collagen fibers on the micron scale. Collagen scaffold materials fabricated from the device will provide contact-guided growth of neuronal cultures. Fibers composed of different weight percentages, 75, 2, and 3.4 wt% collagen dispersions, were used to validate Schwann cell alignment along the fibers. Interestingly, the different concentrations of extruded collagen dispersions demonstrated unique morphologies and directed growth patterns of Schwann cells.

Original language	English (US)
Title of host publication	2011 IEEE 37th Annual Northeast Bioengineering Conference, NEBEC 2011
DOIs	https://doi.org/10.1109/NEBC.2011.5778585
State	Published - Jun 16 2011
Event	37th Annual Northeast Bioengineering Conference, NEBEC 2011 - Troy, NY, United States Duration: Apr 1 2011 → Apr 3 2011

Other

Other	37th Annual Northeast Bioengineering Conference, NEBEC 2011
Country/Territory	United States
City	Troy, NY
Period	4/1/11 → 4/3/11

All Science Journal Classification (ASJC) codes

Bioengineering

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10.1109/NEBC.2011.5778585

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title = "Design and characterization of a controlled wet spinning device for collagen fiber fabrication for neural tissue engineering",

abstract = "Type I collagen was extruded into well-defined fibers using a novel controlled wet spinning device. The device significantly improved the yield of collagen fibers on the micron scale. Collagen scaffold materials fabricated from the device will provide contact-guided growth of neuronal cultures. Fibers composed of different weight percentages, 75, 2, and 3.4 wt% collagen dispersions, were used to validate Schwann cell alignment along the fibers. Interestingly, the different concentrations of extruded collagen dispersions demonstrated unique morphologies and directed growth patterns of Schwann cells.",

author = "DeRosa, {K. E.} and Siriwardane, {M. L.} and Bryan Pfister",

year = "2011",

month = jun,

day = "16",

doi = "10.1109/NEBC.2011.5778585",

language = "English (US)",

isbn = "9781612848273",

booktitle = "2011 IEEE 37th Annual Northeast Bioengineering Conference, NEBEC 2011",

note = "37th Annual Northeast Bioengineering Conference, NEBEC 2011 ; Conference date: 01-04-2011 Through 03-04-2011",

}

DeRosa, KE, Siriwardane, ML & Pfister, B 2011, Design and characterization of a controlled wet spinning device for collagen fiber fabrication for neural tissue engineering. in 2011 IEEE 37th Annual Northeast Bioengineering Conference, NEBEC 2011., 5778585, 37th Annual Northeast Bioengineering Conference, NEBEC 2011, Troy, NY, United States, 4/1/11. https://doi.org/10.1109/NEBC.2011.5778585

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T1 - Design and characterization of a controlled wet spinning device for collagen fiber fabrication for neural tissue engineering

AU - DeRosa, K. E.

AU - Siriwardane, M. L.

AU - Pfister, Bryan

PY - 2011/6/16

Y1 - 2011/6/16

N2 - Type I collagen was extruded into well-defined fibers using a novel controlled wet spinning device. The device significantly improved the yield of collagen fibers on the micron scale. Collagen scaffold materials fabricated from the device will provide contact-guided growth of neuronal cultures. Fibers composed of different weight percentages, 75, 2, and 3.4 wt% collagen dispersions, were used to validate Schwann cell alignment along the fibers. Interestingly, the different concentrations of extruded collagen dispersions demonstrated unique morphologies and directed growth patterns of Schwann cells.

AB - Type I collagen was extruded into well-defined fibers using a novel controlled wet spinning device. The device significantly improved the yield of collagen fibers on the micron scale. Collagen scaffold materials fabricated from the device will provide contact-guided growth of neuronal cultures. Fibers composed of different weight percentages, 75, 2, and 3.4 wt% collagen dispersions, were used to validate Schwann cell alignment along the fibers. Interestingly, the different concentrations of extruded collagen dispersions demonstrated unique morphologies and directed growth patterns of Schwann cells.

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U2 - 10.1109/NEBC.2011.5778585

DO - 10.1109/NEBC.2011.5778585

M3 - Conference contribution

AN - SCOPUS:79958693796

SN - 9781612848273

BT - 2011 IEEE 37th Annual Northeast Bioengineering Conference, NEBEC 2011

T2 - 37th Annual Northeast Bioengineering Conference, NEBEC 2011

Y2 - 1 April 2011 through 3 April 2011

ER -

Design and characterization of a controlled wet spinning device for collagen fiber fabrication for neural tissue engineering

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