Development of finite element rat head model to study the effect of incident pressure and skull rigidity under blast-induced biomechanical loading

A. Sundaramurthy, N. Chandra

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Blast waves generated by improvised explosive devices (IEDs) cause traumatic brain injury (TBI) in soldiers and civilians. Currently, in vivo animal models are extensively used to study blast TBI, to identify mechanisms of injury, and to develop injury thresholds. This work focuses on the study of the effect of Incident Pressure (IP), skull rigidity on the measured Intracranial Pressure (ICP) and maximum principle strain measured on the skull using a validated finite element model of the rat head. Our results indicate that the ICP has a negative correlation with the skull rigidity; i.e., with increase in the skull rigidity the ICP tends to decrease. Similarly, ICP linearly increases with an increase in the IP. Finally, the strain has a negative non linear relationship with the skull rigidity.

Original languageEnglish (US)
Title of host publicationASME 2013 Summer Bioengineering Conference, SBC 2013
DOIs
StatePublished - Dec 1 2013
Externally publishedYes
EventASME 2013 Summer Bioengineering Conference, SBC 2013 - Sunriver, OR, United States
Duration: Jun 26 2013Jun 29 2013

Publication series

NameASME 2013 Summer Bioengineering Conference, SBC 2013
Volume1 B

Other

OtherASME 2013 Summer Bioengineering Conference, SBC 2013
CountryUnited States
CitySunriver, OR
Period6/26/136/29/13

All Science Journal Classification (ASJC) codes

  • Bioengineering
  • Biotechnology
  • Mechanical Engineering

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