DNA Solution Conformation via Infrared Circular Dichroism: Experimental and Theoretical Results for B-Family Polymers

Wenxin Zhong, Miriam Gulotta, Dixie J. Goss, Max Diem

Research output: Contribution to journalArticlepeer-review

58 Scopus citations

Abstract

Infrared (vibrational) circular dichroism (VCD) has been observed for the DNA models d(CG)5, poly(dG-dC)•poly(dG-dC), poly(dG)•poly(dC), poly(dA-dT)•poly(dA-dT), and poly(dA)•poly(dT) in the B-conformation in buffered, aqueous solution. The observed results are quantitatively interpreted in terms of the exciton model for coupled carbonyl stretching vibrational states.

Original languageEnglish (US)
Pages (from-to)7485-7491
Number of pages7
JournalBiochemistry
Volume29
Issue number32
DOIs
StatePublished - Aug 1 1990
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Biochemistry

Fingerprint Dive into the research topics of 'DNA Solution Conformation via Infrared Circular Dichroism: Experimental and Theoretical Results for B-Family Polymers'. Together they form a unique fingerprint.

Cite this