Dynamic response of brain subjected to blast loadings: Influence of frequency ranges

Mehdi S. Chafi, Shailesh Ganpule, Linxia Gu, Namas Chandra

Research output: Contribution to journalArticlepeer-review

27 Scopus citations


Blast wave induced a frequency spectrum and large deformation of the brain tissue. In this study, new material parameters for the brain material are determined from the experimental data pertaining to these large strain amplitudes and wide frequencies ranging (from 0.01 Hz to 10 MHz) using genetic algorithms. Both hyperelastic and viscoelastic behavior of the brain are implemented into 2D finite element models and the dynamic responses of brain are evaluated. The head, composed of triple layers of the skull, including two cortical layers and a middle dipole sponge-like layer, the dura, cerebrospinal fluid (CSF), the pia mater and the brain, is utilized to assess the effects of material model. The results elucidated that frequency ranges of the material play an important role in the dynamic response of the brain under blast loading conditions. An appropriate material model of the brain is essential to predict the blast-induced brain injury.

Original languageEnglish (US)
Pages (from-to)803-823
Number of pages21
JournalInternational Journal of Applied Mechanics
Issue number4
StatePublished - Dec 2011
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • General Materials Science
  • Mechanics of Materials
  • Mechanical Engineering


  • Brain
  • blast wave
  • finite strain
  • high frequency
  • hyper-viscoelastic material model


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