Effect of frequency and electrode configuration on yeast cells subjected to traveling electric fields

Sai Chaitanya Nudurupati, Pushpendra Singh, Nadine Aubry

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

There is great interest in trapping and manipulating small sized particles such as biological, glass, polymer and carbonaceous particles suspended in a liquid. One way to trap such micro/nano sized particles is by means of a microfluidic chamber equipped with electrodes at the bottom and thus generating conventional dielectrophoresis based on an electric field of spatially varying magnitude. In this work, we explore the use of traveling wave dielectrophoresis induced by an electric field of spatially varying phase, which offers both particle capturing/separation and transport capabilities (without having to pump the fluid itself). Particles are subjected to electrostatic and hydrodynamic forces and torques that are computed solving trie full equations of motion for both the fluid and the particles without any modeling (from first principles) and using a finite element scheme based on the Distributed Lagrange Multiplier (DLM) method. We consider two typical microfluidic channels (MEMS devices) with electrodes embedded in the bottom wall. It is found that the motion and destination of the particles strongly depend on the frequency dependent complex Clausius-Mossotti factor (the mismatch between the particles and fluid electric properties), and that the hydrodynamic and electrostatic particle-particle interactions play a crucial role on the particles dynamics. These conclusions are demonstrated on model particles having the properties of yeast cells.

Original languageEnglish (US)
Title of host publication2006 ASME Joint U.S.-European Fluids Engineering Summer Meeting, FEDSM 2006
StatePublished - Dec 1 2006
Event2006 2nd ASME Joint U.S.-European Fluids Engineering Summer Meeting, FEDSM 2006 - Miami, FL, United States
Duration: Jul 17 2006Jul 20 2006

Publication series

Name2006 ASME Joint U.S.-European Fluids Engineering Summer Meeting, FEDSM 2006
Volume2006

Other

Other2006 2nd ASME Joint U.S.-European Fluids Engineering Summer Meeting, FEDSM 2006
CountryUnited States
CityMiami, FL
Period7/17/067/20/06

All Science Journal Classification (ASJC) codes

  • Engineering(all)

Fingerprint Dive into the research topics of 'Effect of frequency and electrode configuration on yeast cells subjected to traveling electric fields'. Together they form a unique fingerprint.

Cite this