Endocrine disrupting chemicals and reproductive disorders in women, men, and animal models

Mary Jo Laws, Alison M. Neff, Emily Brehm, Genoa R. Warner, Jodi A. Flaws

Research output: Chapter in Book/Report/Conference proceedingChapter

32 Scopus citations

Abstract

This chapter covers the known effects of endocrine disrupting chemicals (EDCs) on reproductive disorders. The EDCs represented are highly studied, including plasticizers (bisphenols and phthalates), chemicals in personal care products (parabens), persistent environmental contaminants (polychlorinated biphenyls), and chemicals in pesticides or herbicides. Both female and male reproductive disorders are reviewed in the chapter. Female disorders include infertility/subfertility, irregular reproductive cycles, early menopause, premature ovarian insufficiency, polycystic ovarian syndrome, endometriosis, and uterine fibroids. Male disorders include infertility/subfertility, cryptorchidism, and hypospadias. Findings from both human and animal studies are represented.

Original languageEnglish (US)
Title of host publicationEndocrine-Disrupting Chemicals
EditorsLaura N. Vandenberg, Judith L. Turgeon
PublisherAcademic Press Inc.
Pages151-190
Number of pages40
ISBN (Print)9780128234662
DOIs
StatePublished - Jan 2021
Externally publishedYes

Publication series

NameAdvances in Pharmacology
Volume92
ISSN (Print)1054-3589
ISSN (Electronic)1557-8925

All Science Journal Classification (ASJC) codes

  • Pharmacology

Keywords

  • Bisphenol
  • Endocrine disrupting chemical
  • Fertility
  • Paraben
  • Perfluorochemical
  • Pesticides
  • Phthalate
  • Polychlorinated biphenyls
  • Reproduction
  • Reproductive system health

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