Enhanced fluorescence through the incorporation of nanocones/gaps into a plasmonic gratings sensor platform

Aaron Wood, Sheila Grant, Sagnik Basuray, Avinash Pathak, Sangho Bok, Cherian Mathai, Keshab Gangopadhyay, Shubhra Gangopadhyay

Research output: Chapter in Book/Report/Conference proceedingConference contribution

3 Scopus citations


In this article, a novel plasmonic grating sensor platform was developed and tested for feasibility in sensor applications using a "lights-on" fluorescence based DNA sensor. The sensor platform combined the fluorescence enhancement of a grating-based plasmonic platform with the electric field intensifying effects of nano-scale cones and cavities. The gratings were made through a microcontact printing process that replicated HD-DVD discs in polymethylsilsesquioxane (PMSSQ) and coated in a thin gold film. Nanocavities were incorporated into the sensor platform during the printing process and nanocones were incorporated during the 100 nm gold deposition process. Fluorescently-tagged single-strand (SS) DNA molecules were immobilized onto the surface and were designed such that the molecules would fluoresce when bound to a complementary sequence. Sensor substrates were imaged after exposure to a mismatched and matched oligomer to quantify the fluorescence enhancement of the sensor. Much higher fluorescence intensity was observed on all of the plasmonic structures as compared to flat gold.

Original languageEnglish (US)
Title of host publicationIEEE SENSORS 2014, Proceedings
EditorsFrancisco J. Arregui
PublisherInstitute of Electrical and Electronics Engineers Inc.
Number of pages4
ISBN (Electronic)9781479901616
StatePublished - Dec 12 2014
Externally publishedYes
Event13th IEEE SENSORS Conference, SENSORS 2014 - Valencia, Spain
Duration: Nov 2 2014Nov 5 2014

Publication series

NameProceedings of IEEE Sensors
ISSN (Print)1930-0395
ISSN (Electronic)2168-9229


Conference13th IEEE SENSORS Conference, SENSORS 2014

All Science Journal Classification (ASJC) codes

  • Electrical and Electronic Engineering


  • Aptamer
  • Fluorescence
  • Grating
  • Microcontact
  • Nanocavity
  • Nanocone
  • Plasmonic


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