Abstract
Owing to their unique afterglow ability, long-wavelength light activatable persistent luminescence (PersL) nanoparticles (PLNPs) have been emerging as an important category of imaging probes. Long-wavelength LED light has been shown to be effective in recharging these nanoparticles. However, finding a simple and effective method to amplify such renewable PersL signals under long-wavelength light is still a key challenge. Herein, we discovered that a dye-sensitization strategy was able to effectively boost the renewable PersL signals of the NIR emitting ZnGa2O4:Cr3+ (ZGC)) under long-wavelength LED light. Moreover, as a proof-of-principle tumorectomy demonstration, this new class of dye sensitized ZGC enabled simultaneous intraoperative anatomic tumor navigation and effective microscopic detection of tumor cells in pathological diagnosis.
Original language | English (US) |
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Pages (from-to) | 15886-15890 |
Number of pages | 5 |
Journal | Angewandte Chemie - International Edition |
Volume | 60 |
Issue number | 29 |
DOIs | |
State | Published - Jul 12 2021 |
Externally published | Yes |
All Science Journal Classification (ASJC) codes
- Catalysis
- General Chemistry
Keywords
- dye sensitization
- guided surgery
- imaging
- near infrared
- persistent luminescence