Evolving role of biomaterials in diagnostic and therapeutic radiation oncology

Siyu Shi; Ravi Vissapragada; Joseph Abi Jaoude; Caroline Huang; Anmol Mittal; Elisa Liu; Jim Zhong; Vivek Kumar

doi:10.1016/j.bioactmat.2020.01.011

Evolving role of biomaterials in diagnostic and therapeutic radiation oncology

Siyu Shi, Ravi Vissapragada, Joseph Abi Jaoude, Caroline Huang, Anmol Mittal, Elisa Liu, Jim Zhong, Vivek Kumar

Bio-Medical Engineering

Research output: Contribution to journal › Review article › peer-review

32 Scopus citations

Abstract

Radiation therapy to treat cancer has evolved significantly since the discovery of x-rays. Yet, radiation therapy still has room for improvement in reducing side effects and improving control of cancer. Safer and more effective delivery of radiation has led us to novel techniques and use of biomaterials. Biomaterials in combination with radiation and chemotherapy have started to appear in pre-clinical explorations and clinical applications, with many more on the horizon. Biomaterials have revolutionized the field of diagnostic imaging, and now are being cultivated into the field of theranostics, combination therapy, and tissue protection. This review summarizes recent development of biomaterials in radiation therapy in several application areas.

Original language	English (US)
Pages (from-to)	233-240
Number of pages	8
Journal	Bioactive Materials
Volume	5
Issue number	2
DOIs	https://doi.org/10.1016/j.bioactmat.2020.01.011
State	Published - Jun 2020

All Science Journal Classification (ASJC) codes

Biotechnology
Biomaterials
Biomedical Engineering

Keywords

Biomaterials
Nanoparticles
Radiation therapy
Self-assembly
Theranostics

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10.1016/j.bioactmat.2020.01.011

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abstract = "Radiation therapy to treat cancer has evolved significantly since the discovery of x-rays. Yet, radiation therapy still has room for improvement in reducing side effects and improving control of cancer. Safer and more effective delivery of radiation has led us to novel techniques and use of biomaterials. Biomaterials in combination with radiation and chemotherapy have started to appear in pre-clinical explorations and clinical applications, with many more on the horizon. Biomaterials have revolutionized the field of diagnostic imaging, and now are being cultivated into the field of theranostics, combination therapy, and tissue protection. This review summarizes recent development of biomaterials in radiation therapy in several application areas.",

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T1 - Evolving role of biomaterials in diagnostic and therapeutic radiation oncology

AU - Shi, Siyu

AU - Vissapragada, Ravi

AU - Abi Jaoude, Joseph

AU - Huang, Caroline

AU - Mittal, Anmol

AU - Liu, Elisa

AU - Zhong, Jim

AU - Kumar, Vivek

PY - 2020/6

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N2 - Radiation therapy to treat cancer has evolved significantly since the discovery of x-rays. Yet, radiation therapy still has room for improvement in reducing side effects and improving control of cancer. Safer and more effective delivery of radiation has led us to novel techniques and use of biomaterials. Biomaterials in combination with radiation and chemotherapy have started to appear in pre-clinical explorations and clinical applications, with many more on the horizon. Biomaterials have revolutionized the field of diagnostic imaging, and now are being cultivated into the field of theranostics, combination therapy, and tissue protection. This review summarizes recent development of biomaterials in radiation therapy in several application areas.

AB - Radiation therapy to treat cancer has evolved significantly since the discovery of x-rays. Yet, radiation therapy still has room for improvement in reducing side effects and improving control of cancer. Safer and more effective delivery of radiation has led us to novel techniques and use of biomaterials. Biomaterials in combination with radiation and chemotherapy have started to appear in pre-clinical explorations and clinical applications, with many more on the horizon. Biomaterials have revolutionized the field of diagnostic imaging, and now are being cultivated into the field of theranostics, combination therapy, and tissue protection. This review summarizes recent development of biomaterials in radiation therapy in several application areas.

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KW - Nanoparticles

KW - Radiation therapy

KW - Self-assembly

KW - Theranostics

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Evolving role of biomaterials in diagnostic and therapeutic radiation oncology

Abstract

All Science Journal Classification (ASJC) codes

Keywords

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