Fabrication and characterization of zein–bioactive glass scaffolds

Shiva Naseri; Jasmin Hum; William Cole Lepry; Amir Kamal Miri; Showan Najdat Nazhat; Aldo Roberto Boccaccini

doi:10.1680/bbn.14.00025

Fabrication and characterization of zein–bioactive glass scaffolds

Shiva Naseri, Jasmin Hum, William Cole Lepry, Amir Kamal Miri, Showan Najdat Nazhat, Aldo Roberto Boccaccini

Research output: Contribution to journal › Article › peer-review

12 Scopus citations

Abstract

Plant proteins show advantages over animal-based proteins for biomaterial applications attributable to their ease of availability and suitable biodegradability. In this study, composite foams based on zein and 45S5 bioactive glass (BG) particles were produced through salt leaching for potential applications in bone tissue engineering (BTE) applications. Different characterization techniques were used including scanning electron microscopy for morphological and microstructural analysis, ATR-FTIR spectroscopy and X-ray diffraction for composition characterization and mechanical tests. Zein–BG composite scaffolds demonstrate enhanced bioactivity with a compressive modulus and strength around 5·7 MPa and 1·9 MPa, respectively. Zein–BG composite scaffolds constitute a new bioactive material with potential applications in BTE.

Original language	English (US)
Pages (from-to)	73-78
Number of pages	6
Journal	Bioinspired, Biomimetic and Nanobiomaterials
Volume	4
Issue number	1
DOIs	https://doi.org/10.1680/bbn.14.00025
State	Published - Mar 1 2015
Externally published	Yes

All Science Journal Classification (ASJC) codes

Biomaterials
General Engineering

Keywords

Bioactive glass
Bioactivity
Composite materials
Scaffolds
Zein

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10.1680/bbn.14.00025

Cite this

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AU - Naseri, Shiva

AU - Hum, Jasmin

AU - Cole Lepry, William

AU - Kamal Miri, Amir

AU - Najdat Nazhat, Showan

AU - Boccaccini, Aldo Roberto

PY - 2015/3/1

Y1 - 2015/3/1

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AB - Plant proteins show advantages over animal-based proteins for biomaterial applications attributable to their ease of availability and suitable biodegradability. In this study, composite foams based on zein and 45S5 bioactive glass (BG) particles were produced through salt leaching for potential applications in bone tissue engineering (BTE) applications. Different characterization techniques were used including scanning electron microscopy for morphological and microstructural analysis, ATR-FTIR spectroscopy and X-ray diffraction for composition characterization and mechanical tests. Zein–BG composite scaffolds demonstrate enhanced bioactivity with a compressive modulus and strength around 5·7 MPa and 1·9 MPa, respectively. Zein–BG composite scaffolds constitute a new bioactive material with potential applications in BTE.

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Fabrication and characterization of zein–bioactive glass scaffolds

Abstract

All Science Journal Classification (ASJC) codes

Keywords

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