Feasibility of neural stimulation with floating-light-activated microelectrical stimulators

Ammar Abdo, Mesut Sahin

Research output: Contribution to journalArticlepeer-review

13 Scopus citations


Neural microstimulation is becoming a powerful tool for the restoration of impaired functions in the central nervous system. Microelectrode arrays with fine wire interconnects have traditionally been used in the development of these neural prosthetic devices. However, these interconnects are usually the most vulnerable part of the neuroprosthetic implant that can eventually cause the device to fail. In this paper, we investigate the feasibility of floating-light-activated microelectrical stimulators (FLAMES) for wireless neural stimulation. A computer model was developed to simulate the micro stimulators for typical requirements of neural activation in the human white and gray matters. First, the photon densities due to a circular laser beam were simulated in the neural tissue at near-infrared (NIR) wavelengths. Temperature elevation in the tissue was calculated and the laser power was retrospectively adjusted to 325 and 250 mW/cm2 in the gray and white matters, respectively, to limit \Delta {\rm T}to 0.5 \circC. Total device area of the FLAMES increased with all parameters considered but decreased with the output voltage. We conclude that the number of series photodiodes in the device can be used as a free parameter to minimize the device size. The results suggest that floating, optically activated stimulators are feasible at submillimeter sizes for the activation of the brain cortex or the spinal cord.

Original languageEnglish (US)
Article number5740619
Pages (from-to)179-188
Number of pages10
JournalIEEE Transactions on Biomedical Circuits and Systems
Issue number2
StatePublished - Apr 2011

All Science Journal Classification (ASJC) codes

  • Biomedical Engineering
  • Electrical and Electronic Engineering


  • Neural microstimulation
  • wireless microstimulators


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