Forecasting influenza activity using machine-learned mobility map

Srinivasan Venkatramanan, Adam Sadilek, Arindam Fadikar, Christopher L. Barrett, Matthew Biggerstaff, Jiangzhuo Chen, Xerxes Dotiwalla, Paul Eastham, Bryant Gipson, Dave Higdon, Onur Kucuktunc, Allison Lieber, Bryan L. Lewis, Zane Reynolds, Anil K. Vullikanti, Lijing Wang, Madhav Marathe

Research output: Contribution to journalArticlepeer-review

33 Scopus citations


Human mobility is a primary driver of infectious disease spread. However, existing data is limited in availability, coverage, granularity, and timeliness. Data-driven forecasts of disease dynamics are crucial for decision-making by health officials and private citizens alike. In this work, we focus on a machine-learned anonymized mobility map (hereon referred to as AMM) aggregated over hundreds of millions of smartphones and evaluate its utility in forecasting epidemics. We factor AMM into a metapopulation model to retrospectively forecast influenza in the USA and Australia. We show that the AMM model performs on-par with those based on commuter surveys, which are sparsely available and expensive. We also compare it with gravity and radiation based models of mobility, and find that the radiation model’s performance is quite similar to AMM and commuter flows. Additionally, we demonstrate our model’s ability to predict disease spread even across state boundaries. Our work contributes towards developing timely infectious disease forecasting at a global scale using human mobility datasets expanding their applications in the area of infectious disease epidemiology.

Original languageEnglish (US)
Article number726
JournalNature communications
Issue number1
StatePublished - Dec 1 2021
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • General Chemistry
  • General Biochemistry, Genetics and Molecular Biology
  • General Physics and Astronomy


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