Abstract
Freehand optical coherence tomography (OCT) systems without mechanical scanners can offer greater freedom to access and image sites of interest. However, the scanning velocity during freehand scan is irregular; therefore pseudo B-scan images obtained by stacking sequentially acquired A-scans have a non-uniform spatial sampling rate in the lateral dimension. In this study, we developed a speckle decorrelation method to estimate lateral displacement between sequentially acquired A-scans and used the information extracted from speckle analysis to correct the time-varying lateral scanning speed. We applied this method to a handheld OCT probe and performed calibration experiments to validate our model. Furthermore we demonstrated distortion-free, freehand OCT imaging of various samples including human tissue, in vivo.
Original language | English (US) |
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Title of host publication | Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XVII |
Volume | 8571 |
DOIs | |
State | Published - May 22 2013 |
Externally published | Yes |
Event | Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XVII - San Francisco, CA, United States Duration: Feb 4 2013 → Feb 6 2013 |
Other
Other | Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XVII |
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Country/Territory | United States |
City | San Francisco, CA |
Period | 2/4/13 → 2/6/13 |
All Science Journal Classification (ASJC) codes
- Electronic, Optical and Magnetic Materials
- Biomaterials
- Atomic and Molecular Physics, and Optics
- Radiology Nuclear Medicine and imaging