Functional MRI as a tool to quantify cortical changes from vision rehabilitation

Yelda Alkan, Tara L. Alvarez, Eun Kim, Rajbir Jaswal, Bharat B. Biswal, Suril Gohel, Vincent R. Vicci

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Convergence insufficiency is a vision dysfunction in which people have difficulties performing visual tasks close to them such as reading. Symptoms include headaches, eye strain, blurred and double vision, and visual fatigue. Four subjects participated in 18 hours of vision rehabilitation consisting of home and laboratory sessions. During a longitudinal study, subjects performed a simple vergence oculomotor learning task during an fMRI experiment. Spatial extent and average correlation were quantified in the following regions of interest: the frontal lobe, parietal lobe, cerebellum, and brainstem. Preliminary data suggest improved neuronal synchronization and recruitment quantified through average correlation and spatial extent respectively when comparing the blood oxygenation level dependent signal before versus after rehabilitation. These changes were sustained during a follow-up session.

Original languageEnglish (US)
Title of host publicationICTAI 2009 - 21st IEEE International Conference on Tools with Artificial Intelligence
Pages762-765
Number of pages4
DOIs
StatePublished - 2009
Event21st IEEE International Conference on Tools with Artificial Intelligence, ICTAI 2009 - Newark, NJ, United States
Duration: Nov 2 2009Nov 5 2009

Publication series

NameProceedings - International Conference on Tools with Artificial Intelligence, ICTAI
ISSN (Print)1082-3409

Other

Other21st IEEE International Conference on Tools with Artificial Intelligence, ICTAI 2009
Country/TerritoryUnited States
CityNewark, NJ
Period11/2/0911/5/09

All Science Journal Classification (ASJC) codes

  • Software
  • Artificial Intelligence
  • Computer Science Applications

Keywords

  • Convergence insufficiency
  • Traumatic brain injury
  • Vision rehabilitation
  • fMRI

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