Functionalization of carbon nanotubes with amines and enzymes

Yubing Wang, Zafar Iqbal, Sanjay V. Malhotra

Research output: Contribution to journalArticlepeer-review

232 Scopus citations


This Letter reports the first example of the functionalization of single wall carbon nanotubes (SWNTs) with an enzyme via the formation of a covalent bond as shown particularly by Fourier transform infrared spectroscopy. Functionalization with enzymes was achieved first by acylation of the nanotubes, and was then followed by amidation. Various primary and secondary achiral and chiral amines were also tethered to the SWNTs by this method. Covalent functionalization of carbon nanotubes offers the architecture for a three-dimensional enzyme array for potential application in biosensor devices.

Original languageEnglish (US)
Pages (from-to)96-101
Number of pages6
JournalChemical Physics Letters
Issue number1-3
StatePublished - Jan 24 2005

All Science Journal Classification (ASJC) codes

  • General Physics and Astronomy
  • Physical and Theoretical Chemistry


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