Galaxy method for the 3-D spatial registration of PET images to Talairach brain atlas

  • A. V. Levy
  • , D. Alexoff
  • , F. Hode
  • , M. Denis
  • , D. Bertollo
  • , A. P. Dhawan
  • , J. Logan
  • , B. Andrews
  • , N. D. Volkow

Research output: Contribution to journalConference articlepeer-review

Abstract

Human brain function is studied by averaging many PET images in order to enhance the signal to noise ratio of weak group-specific patterns caused by medication, illness, or functional activation. Present registration methods by Woods and Friston, (SPM), compute 3 translations and 3 rotations to register each PET image to a reference anatomical atlas using a 6 degree of freedom optimization method. By using only a 2 degree of freedom optimization method, the present method decreases the computing time down to 70 sec in a SUN Sparc2 CPU; this is a speed increment by a factor of 3 to 15 times over previous methods. Experimental results for 24 FDG-PET images also indicate that the present method improves the accuracy of the registration to a mean error of 0.48 mm and a maximum error of 2.47 mm.

Original languageEnglish (US)
Pages (from-to)850-851
Number of pages2
JournalAnnual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings
Volume2
StatePublished - 1996
Externally publishedYes
EventProceedings of the 1996 18th Annual International Conference of the IEEE Engineering in Medicine and Biology Society. Part 2 (of 5) - Amsterdam, Neth
Duration: Oct 31 1996Nov 3 1996

All Science Journal Classification (ASJC) codes

  • Signal Processing
  • Health Informatics
  • Computer Vision and Pattern Recognition
  • Biomedical Engineering

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