TY - GEN
T1 - Graphenated IR screen for detection of human and avian flu viruses
AU - Banerjee, Amrita
AU - Chakraborty, Sumit
AU - Grebel, Haim
PY - 2011
Y1 - 2011
N2 - Targeted drug delivery and screening of drugs with specific affinity to membrane proteins require a good monitoring method. Here we monitor the binding of hemagglutinin (HA) to a model membrane- lipid bilayer- by using Infrared (IR) spectroscopy. IR spectroscopy is a useful spectroscopic tool to assess bio-molecular vibrations and provides with molecular fingerprinting. Yet, in order to achieve such goal, one needs to devise a bio-compatible platform that enhances the respective IR signals. We use graphene-coated IR (G-IR) screens as substrates and demonstrate their usefulness in monitoring the attachment of HA from influenza virus to proper receptors.
AB - Targeted drug delivery and screening of drugs with specific affinity to membrane proteins require a good monitoring method. Here we monitor the binding of hemagglutinin (HA) to a model membrane- lipid bilayer- by using Infrared (IR) spectroscopy. IR spectroscopy is a useful spectroscopic tool to assess bio-molecular vibrations and provides with molecular fingerprinting. Yet, in order to achieve such goal, one needs to devise a bio-compatible platform that enhances the respective IR signals. We use graphene-coated IR (G-IR) screens as substrates and demonstrate their usefulness in monitoring the attachment of HA from influenza virus to proper receptors.
UR - http://www.scopus.com/inward/record.url?scp=84858954425&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84858954425&partnerID=8YFLogxK
U2 - 10.1109/NANO.2011.6144595
DO - 10.1109/NANO.2011.6144595
M3 - Conference contribution
AN - SCOPUS:84858954425
SN - 9781457715143
T3 - Proceedings of the IEEE Conference on Nanotechnology
SP - 354
EP - 357
BT - 2011 11th IEEE International Conference on Nanotechnology, NANO 2011
T2 - 2011 11th IEEE International Conference on Nanotechnology, NANO 2011
Y2 - 15 August 2011 through 19 August 2011
ER -