Growth factor delivery from electrospun materials

Electrospinning is a polymer processing technique that has great potential in the field of tissue engineering because of the generation of non-woven fibrous scaffolds with fiber diameter sizes ranging on the order of nanometers to microns. Electrospun fibers are ideal for the local delivery of soluble molecules such as growth factors because of their high surface area to volume ratio. Maintaining the bioactivity of growth factors during the electrospinning process and immobilizing growth factors on the surface of electrospun fibers have been active areas of research. In this review, we will summarize the advances in growth factor delivery using electrospun materials for tissue engineering applications.